How does magnesium support bone health?

Quick summary

Nearly 60 % of the body’s magnesium sits in the skeleton, where it takes part in mineralisation alongside calcium and vitamin D. EFSA officially recognises its contribution to the maintenance of normal bones: an established claim, not a mere hypothesis.

Key facts

Bone reserve About 60 % of the body’s magnesium is stored in the bones, where it takes part in the structure and metabolism of the tissue.
EFSA claim “Contributes to the maintenance of normal bones”: an officially authorised health claim.
Calcium / vitamin D synergy Magnesium is needed to activate vitamin D, which in turn regulates the absorption of calcium.
Bone cells It modulates the activity of osteoblasts (formation) and osteoclasts (resorption) in bone remodelling.

Key points

  • Magnesium contributes to the maintenance of normal bones: this is an established health claim authorised by EFSA.
  • About 60 % of the body’s magnesium is in bone; it takes part in the mineralisation and remodelling of the skeleton.
  • It acts in synergy with calcium and vitamin D, whose activation and use it conditions.
  • An insufficient status can indirectly affect bone strength, without magnesium alone treating osteoporosis.
Depiction of a bone and magnesium-rich foods illustrating the mineral's role in bone health
About 60 % of the body’s magnesium is stored in the skeleton, where it takes part in mineralisation alongside calcium and vitamin D.

Magnesium is often overshadowed by calcium when bones are discussed, and that is a mistake: it is one of the minerals whose contribution to the maintenance of normal bones is officially recognised by the European Food Safety Authority (EFSA). This article is part of the benefits of magnesium for the body and details how this mineral acts on the skeleton, on its own and in synergy with calcium and vitamin D. For an overview, also read our complete magnesium guide.

What role does magnesium play in the skeleton?

About 60 % of the body’s magnesium is stored in the skeleton, where it takes part directly in the structure and metabolism of bone tissue[1]. On this solid physiological basis, EFSA authorises the claim “magnesium contributes to the maintenance of normal bones”[2]. Unlike other effects often attributed to magnesium, this one is not a marketing promise: it is an established claim.

A player in bone remodelling

Bone is not a static tissue: it is constantly renewed thanks to two populations of cells. Osteoblasts build and mineralise the matrix; osteoclasts resorb the old tissue. Magnesium modulates the activity of both cell types; an imbalance can therefore disrupt this remodelling cycle and, over time, the quality of the bone.

A cofactor of mineralisation

Magnesium also acts as a cofactor for the enzymes involved in bone metabolism. It takes part in the formation of the matrix and conditions the proper use of calcium, directing its deposition into bone rather than into soft tissue. It is this role as a discreet conductor that justifies not thinking of calcium without magnesium.

60 % of the body’s magnesium is held in the bones. This skeletal reserve underlines the close link between magnesium status and bone health, beyond its muscular and nervous role. Source: de Baaij et al., Physiological Reviews 2015

Magnesium, calcium and vitamin D: a bone trio

Bone health does not come down to calcium alone. Magnesium is part of a functional trio in which each nutrient depends on the others.

Magnesium activates vitamin D

Vitamin D must be converted into its active form to regulate the intestinal absorption of calcium. Now several steps of this activation rely on magnesium-dependent enzymes[1]. A magnesium deficiency can therefore hold back the use of vitamin D, and indirectly that of calcium: supplementing with calcium and vitamin D without covering your magnesium needs amounts to neglecting a link in the chain.

A balance, not a competition

Calcium and magnesium are not at odds: they complement each other. Calcium provides the hardness, magnesium takes part in the quality and regulation of mineral deposition. An excess of calcium from supplements can, however, hamper the absorption of magnesium, hence the value of a balanced intake rather than supplementation skewed in favour of a single mineral.

Magnesium deficiency and bone fragility

An insufficient magnesium status can affect the skeleton, but here too one must stay measured about the scope of this observation.

What a deficiency can lead to

A chronic deficiency disrupts bone remodelling and the metabolism of calcium and vitamin D, which can contribute to a lower bone quality. The link between low magnesium status and bone fragility is documented, but magnesium is only one factor among others: osteoporosis results from a combination of age, hormones, physical activity and nutritional intake.

Supporting is not treating

Maintaining a good magnesium status supports normal bones; it does not mean that supplementation treats or cures osteoporosis. The nuance, consistent with the EFSA claim, is essential: we are talking about a contribution to the maintenance of a normal function, not a treatment for an established bone disease.

Warning

A diagnosis of osteoporosis or a proven bone fragility falls within medical care. Magnesium can be part of good nutritional habits, but it replaces neither a clinical work-up nor a prescribed treatment.

How to support your bone capital in practice?

The reference requirement is around 300 to 400 mg of magnesium per day in adults. A varied diet normally covers this intake, alongside an adequate calcium and vitamin D status.

Good food sources

For a well-supplied skeleton, favour:

  • Nuts and seeds such as almonds, Brazil nuts and pumpkin seeds.
  • Green leafy vegetables such as spinach and kale.
  • Legumes such as lentils, chickpeas and black beans.
  • Whole grains such as oats, quinoa and brown rice.

Supplements and absorption factors

If the diet is not enough, a well-dosed and well-tolerated supplement can help, without exceeding the recommended doses so as to avoid digestive upset. A few habits also support magnesium status: limiting alcohol and not over-dosing calcium from supplements, two factors liable to hamper its absorption. In case of doubt, a healthcare professional can assess whether supplementation is appropriate.

Frequently asked questions

Is magnesium really important for the bones?

Yes, and in an officially recognised way. EFSA authorises the claim “magnesium contributes to the maintenance of normal bones”. Nearly 60 % of the body’s magnesium is stored in the skeleton, where it takes part in mineralisation, bone remodelling and the use of calcium and vitamin D. It is one of the minerals whose bone role is best established, beyond calcium alone.

Should magnesium be taken with calcium and vitamin D?

These three nutrients work together. Magnesium is needed to activate vitamin D, which in turn regulates the absorption of calcium. Covering your calcium and vitamin D intakes without minding magnesium amounts to neglecting a link in the chain. The aim is not to supplement everything, but to have a balanced intake, ideally through the diet.

Can a magnesium deficiency cause osteoporosis?

A chronic magnesium deficiency can contribute to lower bone quality by disrupting remodelling and the metabolism of calcium and vitamin D. But magnesium is only one factor among others: osteoporosis also depends on age, hormones, physical activity and the diet as a whole. Maintaining a good status supports normal bones, but does not treat an established osteoporosis.

Which foods to favour for magnesium and the bones?

Nuts and seeds (almonds, Brazil nuts, pumpkin seeds), green leafy vegetables (spinach, kale), legumes (lentils, chickpeas) and whole grains (oats, quinoa, brown rice) are excellent sources. A varied diet covering 300 to 400 mg per day, combined with a good calcium and vitamin D status, supports bone capital.

Is a magnesium supplement needed to protect your bones?

For most adults, a varied diet is enough. A supplement may be justified in the case of insufficient intake or increased needs, provided the doses are respected to avoid digestive upset. Limiting alcohol and not over-dosing calcium from supplements also helps the absorption of magnesium. In the case of bone fragility, medical advice remains indispensable.

Sources & references

3 sources
  1. de Baaij JHF, Hoenderop JGJ, Bindels RJM — Magnesium in man: implications for health and disease — Physiological Reviews, 2015 (review, DOI 10.1152/physrev.00012.2014)
  2. EFSA NDA Panel — Scientific Opinion on Dietary Reference Values for magnesium — EFSA Journal, 2015 (official opinion; claim “maintenance of normal bones”, DOI 10.2903/j.efsa.2015.4186)
  3. Gröber U, Schmidt J, Kisters K — Magnesium in Prevention and Therapy — Nutrients, 2015 (review, DOI 10.3390/nu7095388)

Article published on , last updated on .